刘利静
E-Mail: ljliu@sdu.edu.cn
教育背景
2001.9-2005.7 河北师范大学,本科;
2005.9-2011.7 中国科学院遗传与发育生物学研究所,遗传学博士。
工作经历
2011.7-2011.11 中国科学院遗传与发育生物学研究所,博士后;
2011.11-2016.11 美国杜克大学,博士后;
2016.11-2017.8 美国杜克大学,研究科学家;
2017.12-至今 山东大学,教授。
研究方向
本课题组以拟南芥和高粱为研究材料,利用正向/反向遗传学、生物化学、基因组学、生物信息学等手段深入研究植物抗逆胁迫的作用机理。通过筛选和分子设计创制耐逆高粱新品系。
1.植物抗逆境胁迫的分子机制研究;
2. 耐逆高粱新种质的创制。
主持课题
国家重点研发计划子课题 2023-2028
国家重点研发计划子课题 2022-2027
国家自然科学基金 2021-2023
山东省自然科学基金 2021-2023
山东大学“齐鲁青年学者”建设经费 2017-2022
代表性文章(*第一作者;#通讯作者)
1.Zhang, M.*, Li, W.*, Zhang, T.*, Liu, Y., and Liu, L.# (2023). Botrytis cinerea-induced F-box protein 1 enhances disease resistance without fitness costs by inhibiting JAO-mediated jasmonic acid catabolism in Arabidopsis. Mol Plant Accepted
2.Liu, Y.*, Gong, T., Kong, X., Sun, J., and Liu, L.# (2023). XYLEM CYSTEINE PEPTIDASE 1 and its inhibitor CYSTATIN 6 regulate pattern-triggered immunity by modulating the stability of the NADPH oxidase RBOHD. Plant Cell
3.Li, J.*, Pan, W., Zhang, S., Ma, G., Li, A., Zhang, H.#, and Liu, L.# (2023). A rapid and highly efficient sorghum transformation strategy using GRF4-GIF1/ternary vector system. Plant J
4.Pan, W.*, Li, W.*, Liu, L.#, and Zhang, H.# (2022). Antiviral strategies: What can we learn from natural reservoirs? J Integr Plant Biol
5.Kong, X.*, Pan, W.*, Sun, N., Zhang, T., Liu, L.#, and Zhang, H.# (2021). GLABRA2-based selection efficiently enriches Cas9-generated nonchimeric mutants in the T1 generation. Plant Physiol
其他文章(部分)
1.Kong, X.J.*, Pan, W.B., Zhang, T.Y., Liu, L.J.#, and Zhang, H.W.# (2023). A simple and efficient strategy to produce transgene-free gene edited plants in one generation using paraquat resistant 1 as a selection marker. Front Plant Sci 13.
2.Wang, X.*, Yan, F.*, Ma, G., Li, A., and Liu, L.# (2023). The diverse functions of Pseudomonas syringae syringae van Hall effectors in regulating the plant immune response. Phytopathol Res
3.Sun, W.*, Zhang, H.*, Yang, S.*, Liu, L.*, Xie, P., Li, J., Zhu, Y., Ouyang, Y., Xie, Q., Zhang, H., et al. (2023). Genetic modification of Ggamma subunit AT1 enhances salt-alkali tolerance in main graminaceous crops. Natl Sci Rev
4.Chen, T., Xu, G., Mou, R., Greene, G.H., Liu, L., Motley, J., and Dong, X. (2023). Global translational induction during NLR-mediated immunity in plants is dynamically regulated by CDC123, an ATP-sensitive protein. Cell Host Microbe
5.Wang, Y., Yue, J., Yang, N., Zheng, C., Zheng, Y., Wu, X., Yang, J., Zhang, H., Liu, L., Ning, Y., et al. (2023). An ERAD-related ubiquitin-conjugating enzyme boosts broad-spectrum disease resistance and yield in rice. Nat Food.
6.Sun, X.*, Li, A., Ma, G., Zhao, S., and Liu, L.# (2022). Transcriptome analysis provides insights into the bases of salicylic acid-induced resistance to anthracnose in sorghum. Plant Mol Biol
7.Li, A.*, #, Sun, X., and Liu, L.# (2022). Action of Salicylic Acid on Plant Growth. Front Plant Sci
8.Li, W.*, Zhang, M.*, Zhang, T., Liu, Y., and Liu, L.# (2022). Arabidopsis Cys2/His2 Zinc Finger Transcription Factor ZAT18 Modulates the Plant Growth-Defense Tradeoff. Int J Mol Sci
9.Liu, G., Liang, J., Lou, L., Tian, M., Zhang, X., Liu, L., Zhao, Q., Xia, R., Wu, Y., Xie, Q., et al. (2022). The deubiquitinases UBP12 and UBP13 integrate with the E3 ubiquitin ligase XBAT35.2 to modulate VPS23A stability in ABA signaling. Sci Adv
10.Sun, N.*, Kong, X.*, Liu, Y., Gong, T., Gu, X., and Liu, L.# (2021). The THO/TREX Complex Active in Alternative Splicing Mediates Plant Responses to Salicylic Acid and Jasmonic Acid. Int J Mol Sci
11.Gu, X.*, Liu, L.#, and Zhang, H.# (2021). Transgene-free Genome Editing in Plants. Front Genome Ed
12.Huang, X.X., Wang, Y., Lin, J.S., Chen, L., Li, Y.J., Liu, Q., Wang, G.F., Xu, F., Liu, L., and Hou, B.K. (2021). A novel pathogen-responsive glycosyltransferase UGT73C7 mediates the redirection of phenylpropanoid metabolism and promotes SNC1-dependent Arabidopsis immunity. Plant J.
13.Kong, X.P., Zhang, C.L., Zheng, H.H., Sun, M., Zhang, F., Zhang, M.Y., Cui, F.H., Lv, D.P., Liu, L.J., Guo, S.Y., et al. (2020). Antagonistic Interaction between Auxin and SA Signaling Pathways Regulates Bacterial Infection through Lateral Root in Arabidopsis. Cell Rep
14.Pan, W., Lin, B., Yang, X., Liu, L., Xia, R., Li, J., Wu, Y., and Xie, Q. (2020). The UBC27-AIRP3 ubiquitination complex modulates ABA signaling by promoting the degradation of ABI1 in Arabidopsis. Proc Natl Acad Sci U S A
15.Yoo, H., Greene, G.H., Yuan, M., Xu, G., Burton, D., Liu, L., Marques, J., and Dong, X. (2020). Translational Regulation of Metabolic Dynamics during Effector-Triggered Immunity. Mol Plant
16.Wang, W., Withers, J., Li, H., Zwack, P.J., Rusnac, D.V., Shi, H., Liu, L.J., Yan, S.P., Hinds, T.R., Guttman, M., et al. (2020). Structural basis of salicylic acid perception byArabidopsisNPR proteins. Nature
17.谷晓勇,刘扬,刘利静 (2020). 植物激素水杨酸生物合成和信号转导研究进展. 遗传
18.Liu, L., Sonbol, F.M., Huot, B., Gu, Y., Withers, J., Mwimba, M., Yao, J., He, S.Y., and Dong, X. (2016). Salicylic acid receptors activate jasmonic acid signalling through a non-canonical pathway to promote effector-triggered immunity. Nat Commun
19.Cui, F.*, Liu, L.*, Zhao, Q., Zhang, Z., Li, Q., Lin, B., Wu, Y., Tang, S., and Xie, Q. (2012). Arabidopsis ubiquitin conjugase UBC32 is an ERAD component that functions in brassinosteroid-mediated salt stress tolerance. Plant Cell
20.Liu, L., Cui, F., Li, Q., Yin, B., Zhang, H., Lin, B., Wu, Y., Xia, R., Tang, S., and Xie, Q. (2011). The endoplasmic reticulum-associated degradation is necessary for plant salt tolerance. Cell Res
21.Liu, L.*, Zhang, Y.*, Tang, S., Zhao, Q., Zhang, Z., Zhang, H., Dong, L., Guo, H., and Xie, Q. (2010). An efficient system to detect protein ubiquitination by agroinfiltration in Nicotiana benthamiana. Plant J